Yang Zhang1, Gytis Balilionis1, Catalina M. Casaru1, Randall E. Schumacker2, Yasmin H. Neggers3, Matthew D. Curtner-Smith1, Mark T. Richardson1, James M. Green4, Phillip A. Bishop1

1The University of Alabama, Department of Kinesiology, Tuscaloosa, USA
2The University of Alabama, Department of Educational Studies in Psychology, Research Methodology, and Counseling, Tuscaloosa, AL, USA
3The University of Alabama, Department of Human Nutrition, Tuscaloosa, AL, USA
4The University of North Alabama, Department of Health, Physical Education and Recreation, Florence, AL, USA

Effect of Menthol on Respiratory and Perceptual Responses to Exercise in Firefighter Protective Gear

Monten. J. Sports Sci. Med. 2015, 4(2), 29-34


Impaired respiration reduces firefighters’ work capacity. This study evaluated the effect of menthol lozenge on respiratory and perceptual responses during exercise in a hot environment. Ten participants wearing firefighter protective gear performed two repeated exercise and rest trials in a counter-balanced order. Exercise consisted of two bouts of 20-min treadmill exercise at 60% of maximal oxygen uptake and one bout of 20-min stepping exercise at a wet bulb global temperature of 35°C. Participants either took 10-mg menthol or control lozenges prior to the beginning of each exercise bout. Respiratory gas exchange, heart rate, thermal sensation, and breathing comfort were continuously recorded. Menthol lozenges significantly increased pulmonary ventilation (menthol: 45.0±6.6 L•min-1 vs. control: 41.4±5.8 L•min-1 and menthol: 52.7±9.7 L•min-1 vs. control: 46.5±7.0 L•min-1, for the 1st and 2nd treadmill exercise, respectively) and oxygen consumption (menthol: 26.7±2.0 ml•kg-1•min-1 vs. control: 25.2±2.3 ml•kg-1•min-1 and menthol: 28.8±2.3 ml•kg-1•min-1 vs. control: 26.9±1.9 ml•kg-1•min-1, for the 1st and 2nd treadmill exercise, respe¬cti¬ve¬ly) (p<0.05). The effect of menthol on respiration disappeared during the stepping exercise (p>0.05). The ventilatory equivalents though were not different throughout the exercise (p>0.05). Ratings of thermal sensation and breathing comfort were not different (p>0.05). It was concluded that menthol could alter breathing pattern and increase respiratory responses during strenuous exercise in the heat. There was no favorable effect of menthol on respiratory or perceptual responses under exercise-heat stress.


Firefighter, protective clothing, respiration, oxygen consumption

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Abadie, B., & Carroll, J. (1993). Effect of facemask vs. mouthpiece use on physiological responses to exercise. Research Quarterly for Exercise and Sport, 64.

Ahijevych, K., & Garrett, B. E. (2004). Menthol pharmacology and its potential impact on cigarette smoking behavior. Nicotine & Tobacco Research, 6 Suppl 1, S17-28.

Beaudin, A. E., Clegg, M. E., Walsh, M. L., & White, M. D. (2009). Adaptation of exercise ventilation during an actively-induced hyperthermia following passive heat acclimation. American Journal of Physiology: Regulatory, Integrative and Comparative Physiology, 297(3), R605-614.

Bilzon, J. L., Scarpello, E. G., Smith, C. V., Ravenhill, N. A., & Rayson, M. P. (2001). Characterization of the metabolic demands of simulated shipboard Royal Navy fire-fighting tasks. Ergonomics, 44(8), 766-780.

Choi, J. H., Shin, J. H., Lee, M. Y., & Chung, I. S. (2014). Pulmonary function decline in firefighters and non-firefighters in South Korea. Annals of Occupational and Environmental Medicine, 26, 9.

Donovan, K., & McConnell, A. (1999). Do fire-fighters develop specific ventilatory responses in order to cope with exercise whilst wearing self-contained breathing apparatus? European Journal of Applied Physiology and Occupational Physiology, 80(2), 107-112.

Eccles, R. (2003). Menthol: effects on nasal sensation of airflow and the drive to breathe. Current Allergy and Asthma Reports, 3(3), 210-214.

Eccles, R., Jawad, M. S., & Morris, S. (1990). The effects of oral administration of (-)-menthol on nasal resistance to airflow and nasal sensation of airflow in subjects suffering from nasal congestion associated with the common cold. Journal of Pharmacy and Pharmacology, 42(9), 652-654.

Eves, N. D., Jones, R. L., & Petersen, S. R. (2005). The influence of the self-contained breathing apparatus (SCBA) on ventilatory function and maximal exercise. Canadian Journal of Applied Physiology, 30(5), 507-519.

Gledhill, N., & Jamnik, V. K. (1992). Characterization of the physical demands of firefighting. Canadian Journal of Sport Sciences, 17(3), 207-213.

Holmer, I., & Gavhed, D. (2007). Classification of metabolic and respiratory demands in fire fighting activity with extreme workloads. Applied Ergonomics, 38(1), 45-52.

Ito, S., Kume, H., Shiraki, A., Kondo, M., Makino, Y., Kamiya, K., & Hasegawa, Y. (2008). Inhibition by the cold receptor agonists menthol and icilin of airway smooth muscle contraction. Pulmonary Pharmacology and Therapeutics, 21(5), 812-817.

Livingstone, S. D., Nolan, R. W., Cain, J. B., & Keefe, A. A. (1994). Effect of working in hot environments on respiratory air temperatures. European Journal of Applied Physiology and Occupational Physiology, 69(2), 98-101.

Louhevaara, V., Smolander, J., Tuomi, T., Korhonen, O., & Jaakkola, J. (1985). Effects of an SCBA on breathing pattern, gas exchange, and heart rate during exercise. Journal of Occupational Medicine, 27(3), 213-216.

Maher, S., Birrell, M., Bonvini, S., Wortley, M., Dubuis, E., Shala, F., . . . Britton, Z. (2014). P6 Menthol Has Beneficial Effects In The Airways Through A Trpm8-independent Mechanism. Thorax, 69(Suppl 2), A79-A80.

Mundel, T., & Jones, D. A. (2010). The effects of swilling an L(-)-menthol solution during exercise in the heat. European Journal of Applied Physiology, 109(1), 59-65.

Nielsen, R., Gwosdow, A. R., Berglund, L. G., & DuBois, A. B. (1987). The effect of temperature and humidity levels in a protective mask on user acceptability during exercise. American Industrial Hygiene Association Journal, 48(7), 639-645.

Nishino, T., Tagaito, Y., & Sakurai, Y. (1997). Nasal inhalation of l-menthol reduces respiratory discomfort associated with loaded breathing. American Journal of Respiratory and Critical Care Medicine, 156(1), 309-313.

Pollack, M. L., Schmidt, D. H., & Jackson, A. S. (1980). Measurement of cardio-respiratory fitness and body composition in the clinical setting. Comprehensive Therapy, 6(9), 12-27.

Prieto, J. A., Gonzalez, V., Del Valle, M., & Nistal, P. (2013). The influence of age on aerobic capacity and health indicators of three rescue groups. International Journal of Occupational Safety and Ergonomics, 19(1), 19-27.

Roberge, R. J., Kim, J. H., & Coca, A. (2012). Protective facemask impact on human thermoregulation: an overview. Annals of Occupational Hygiene, 56(1), 102-112.

Romet, T. T., & Frim, J. (1987). Physiological responses to fire fighting activities. European Journal of Applied Physiology and Occupational Physiology, 56(6), 633-638.

Smith, D. L., Manning, T. S., & Petruzzello, S. J. (2001). Effect of strenuous live-fire drills on cardiovascular and psychological responses of recruit firefighters. Ergonomics, 44(3), 244-254.

Smith, D. L., Petruzzello, S. J., Kramer, J. M., & Misner, J. E. (1997). The effects of different thermal environments on the physiological and psychological responses of firefighters to a training drill. Ergonomics, 40(4), 500-510.

Walker, A., Driller, M., Argus, C., Cooke, J., & Rattray, B. (2014). The ageing Australian firefighter: an argument for age-based recruitment and fitness standards for urban fire services. Ergonomics, 57(4), 612-621.

Wright, C. E., Laude, E. A., Grattan, T. J., & Morice, A. H. (1997). Capsaicin and neurokinin A-induced bronchoconstriction in the anaesthetised guinea-pig: evidence for a direct action of menthol on isolated bronchial smooth muscle. British Journal of Pharmacology, 121(8), 1645-1650.

Young, A. J., Sawka, M. N., Epstein, Y., Decristofano, B., & Pandolf, K. B. (1987). Cooling different body surfaces during upper and lower body exercise. Journal of Applied Physiology (1985), 63(3), 1218-1223.

Zhang, Y., Balilionis, G., Casaru, C., Geary, C., Schumacker, R. E., Neggers, Y. H., . . . Green, J. M. (2014). Effects of caffeine and menthol on cognition and mood during simulated firefighting in the heat. Applied Ergonomics, 45(3), 510-514.