Plasma Growth Hormone and Prolactin Levels
in Healthy Sedentary Young Men after Short-Term Endurance Training under Hot Environment

İbrahim Cicioglu; Fatih Kiyici

¹Gazi University, School of Physical Education and Sport, Ankara, Turkey
²Ataturk University, School of Physical Education and Sports, Erzurum, Turkey

Plasma Growth Hormone and Prolactin Levels in Healthy Sedentary Young Men after Short-Term Endurance Training under Hot Environment

NIVOI PLAZMINOG HORMONA RASTA I PROKLATINA KOD ZDRAVIH SEDENTARNIH MLADIH LJUDI NAKON KRATKOTRAJNOG TRENINGA U TOPLOM OKRUŽENJU

Monten. J. Sports Sci. Med. 2013, 2(2), 9-13

Abstract

Pituitary hormones play an important role energy expenditure and body temperature regulation during exercise. The aim of the stu¬dy was to investigate the effect of two different endurance training in ambient temperature (30.76 ± 1.71oC and 57.92 ± 5.80% r.h.) on plasma growth hormone (GH) and prolactin (PRL) levels in non-trained healthy subjects. Twenty-four untrained healthy men participated in an 8-wk progressive two different endurance-training program. Subjects were divided into two groups: an in¬ter¬val running group (IR), and continuous running group (CR). Both groups were performed 3 days/wk. Growth hormone, PRL and VO2max levels were assessed at the beginning and the end of the training period. Body temperature (TB) was also measured at the be¬ginning and immediately after each training. The exercise type affected plasma PRL (8.52 vs. 6.50 ng/ml IR and CT groups, P < 0.02) but did not alter plasma GH levels (0.95 vs 0.63 ng/ml IR and CT groups, P>0.38). Plasma GH level at the end of training pro¬gram increased from 0.42 to 1.48 ng/ml and 0.58 to 0.67 ng/ml for IR and CR groups. Expectedly, both training types increased TB, at a greater rate for IR group than CR group. In conclusion, an 8-wk regular exercise result in an increase in plasma PRL level, with¬out altering plasma GH level, which accompanied by elevated body temperature, regardless of the individual’s sporting rou¬ti¬ne. These suggest that untrained individuals could benefit from a regular exercise program as much as those doing the routine sport.

Keywords

GH, PRL, hot temperature, endurance training

Abstract (MNE)

Hipofizini hormini imaju važnu ulogu u potrošnji energije i regulaciji tjelesne temperature tokom vježbanja. Cilj istraživanja bio je da se ispita uticaj dva različita treninga izdržljivosti u sobnoj temperaturi (30.76 ± 1.71oC i 57.92 ± 5.80% r.h.) na nivo plazminog hormona rasta (GH) i proklatina (PRL) kod neobučenih zdravih ispitanika. Dvadesetčetvorica neobučenih zdravih muškaraca učestvovali su u dva različita osmonedjeljna progresivna programa treninga izdržljivosti. Učesnici su bili podijeljeni u dvije grupe: grupu koja je povremeno trčala (IR), i grupu koja je neprestano trčala (CR). Obije grupe su izvodile vježbe 3 dana nedjeljno. Nivo hormona rasta, PRL-a i VO2max procjenjivan je na početku i na kraju perioda treniranja. Tjelesna temperature (TB), takođe je mjerena na početku svakog treninga i odmah nakon istih. Ovaj tip vježbe uticao je na plazmin PRL (8.52 naspram 6.50 ng/ml IR i CT grupe, P < 0.02) ali nije mijenjao nivoe plazminog GH (0.95 naspram 0.63 ng/ml IR i CT grupe, P>0.38). Nivo plazminog GH na kraju programa treniranja povećao se od 0.42 do 1.48 ng/ml i od 0.58 do 0.67 ng/ml za IR i CR grupe. Kao što je očekivano, oba tipa treninga povećala su TB, pri čemu je rast bio veći kod IR grupe nego kod CR grupe. Zaključeno je da je osmonedjeljno redovno vježbanje rezultiralo porastom nivoa plazminog proklatina, ne mijenjajući nivo plazminog hormona rasta, što dalje prati povišena tjelesna temperatura, bez obzira na sportske rutine pojedinca. Ovo nagovještava da neobučeni individualci mogu imati koristi od redovnog programa treniranja u istoj mjeri koliko i oni koji rutinski treniraju.

Keywords (MNE)

hormon rasta, proklatin, visoka temperatura, trening izdržljivosti

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References

1. WILMORE JH, COSTILL DL, KENNEY WL. Physiology of Sport and Exercise (Champaign, IL: Human Kinetics, 2012). – 2. COLLINS KJ, WEINER JS. Endocrinological aspects of exposure to high environmental temperatures. Physiological Reviews, 48 (1968) 785. – 3. FRANCESCONI RP (1988) Endocrinological responses to exercise in stressful environments. Exercise and Sport Sciences Reviews, 16 (1988) 255. – 4. LOW D, PURVIS A, REILLY T, CABLE NT. The prolactin responses to active and passive heating in man. Experimental Physiology, 90(6) (2005) 909. – 5. Wendt D, van Loon LJ, Lichtenbelt WD.. Thermoregulation during exercise in the heat: strategies for maintaining health and performance. Sport Medicine, 37 (2007) 669. – 6. GALLOWAY SDR, MAUGHAN RJ. Effects of ambient temperature on the capacity to perform prolonged cycle exercise in man. Medicine and Science in Sports and Exercise, 29 (1997) 1240. – 7. PARKIN JM, CAREY MF, ZHAO S, FEBBRAIO MA. Effect of ambient temperature on human skeletal muscle metabolism during fatiguing submaximal exercise. Journal of Applied Physiology, 86 (1999) 902. – 8. COYLE EF, MONTAIN S. Thermal and cardiovascular responses to fluid replacement during exercise. In: GISOLFI CV, LAMB DR, NADEL ER (eds) Exercise, Heat and Thermoregulation (Brown & Benchmark, Dubuque, 1993). – 9. BRIDGE MW, ALLEN T, SHARMA A, JONES DA, Effect of ambient temperature on exercise-induced prolactinaemia. Journal of Physiology, 521(P) (1999) 103. – 10. LEPPALUOTO JP, HUTTUNEN J, HIRVONEN A, VAANANEN M, TUOMINEN J, VUORI I, Endocrine effects of repeated sauna bathing. Acta Physiologica Scandinavica, 128 (1986) 467. – 11. JENKINS PJ, Growth hormone and exercise. Clinical Endocrinology, 50 (1999) 683. – 12. HARTMAN ML, Physiological regulators of growth hormone secretion. In: JUUL A, JORGENSEN J (eds) Growth hormone in adults (Cambridge University, Cambridge, 2000). – 13. Van CAUTER E, KERKHOFS M, CAUFRIEZ A, Van ONDERBERGEN A, THORNER MO, COPINSCHI G, A quantitative estimation of growth hormone secretion in normal man: reproducibility and relation to sleep and time of day. Journal of Clinical Endocrinology & Metabolism, 74 (1992) 1441. – 14. PIETROWSKY R, MEYRER R, KERN W, BORN J, FEHM HL, Effects of diurnal sleep on the secretion of cortisol, lutenizing hormone and growth hormone inman. Journal of Clinical Endocrinology & Metabolism, 78 (1994) 683. – 15. KANALEY JA, WELTMAN JY, PIEPER KS, WELTMAN A, HARTMAN ML, Cortisol and growth hormone responses to exercise at different times of day. Journal of Clinical Endocrinology & Metabolism, 86 (2001) 2881. – 16. VIGAS M, CELKO J, KOSKA J, Role of body temperature in exercise-induced growth hormone and prolactin release in nontrained and physically fit subjects. Endocrine Regulations, 34 (2000) 175. – 17. CHRISTENSEN SE, JORGENSEN OL, MOLLER N, SKOV H, Characterization of growth hormone release in response to external heating. Comparison to exercise induced release. Acta Endocrinologica, 107 (1984) 295. – 18. BRISSON GR, PERONNET F, PERRAULT H, BOISVERT P, MASSICOTTE D, GAREAU R, Rolactinotrophic effect of endogenous and exogenous heat loads in human male adults. Journal of Applied Physiology, 70 (1991) 1351. – 19. PRITZLAFF CJ, WIDEMAN L, WELTMAN JY, ABBOTT RD, GUTGESELL ME, HARTMAN ML, VELDHUIS JD, WELTMAN A, Impact of acute exercise intensity on pulsatile growth hormone release in men. Journal of Applied Physiology, 87 (1999) 498. – 20. KARAGIORGOS A, GARCIA JF, BROOKS GA, Growth hormone response to continuous and intermittent exercise. Journal of medicine and science in sports, 11 (1979) 302. – 21. JEZOVA D, KVETNANSKY R, VIGAS M, Sex differences in endocrine response to hyperthermia in sauna. Acta Physiologica Scandinavica, 150 (1994) 293. – 22. BUCKLER JMH, The relationship between changes in plasma growth hormone levels and body temperature occurring with exercise in man. Biomedicine, 19 (1973) 193. – 23. CHRISTENSEN SE, JARGENSEN OL, MALLER N, ORSKOV H, Characterization of growth hormone release in response to external heating. Cornparison to exercise induced release. Acta Endocrinologica, 107 (1984) 295. – 24. CROSS MC, RADOMSKI MW, Van HELDER WP, RHIND SG, SHEPHARD RJ, Endurance exercise with and without a thermal clamp: effects on leucocytes and leucocyte subsets. Journal of Applied Physiology, 81 (1996) 822. – 25. FREWIN DB, FRANTZ AG, DOWNEY JA, The effect of ambient temperature on the growth hormone and prolactin response to exercise. Australian Journal of Experimental Biology & Medical Science, 54 (1976) 97. – 26. RAYNAUD J, CAPDEROU A, MARTINEAUD JP, BORDACHAR J, DURAND J, Intersubject variability in growth hormone time course during different types of work. Journal of Applied Physiology, 55 (1983) 1682. – 27. BRIDGE MW, WELLER AS, RAYSON M, Jones DA, Ambient temperature and the pituitary hormone responses to exercise in humans. Ambient temperature and the pituitary hormone responses to exercise in humans. Experimental Physiology, 88(5) (2003) 627. – 28. WEE J, CHARLTON C, SIMPSON H, JACKSON NC, SHOJAEE-MORADIE F, STOLINSKI M, PENTECOST C, UMPLEBY AM, GH secretion in acute exercise may result in post-exercise lipolysis. Growth Hormone & IGF Research, 15 (2005) 397. – 29. VIGAS M, CELKO J, KOSKA J, Role of body temperature in exercise-induced growth hormone and prolactin release in non-trained and physically fit subjects. Endocrine Regulations, 34 (2000) 175. – 30. ARMSTRONG DW, HATFIELD BD, Hormonal responses to opioid receptor blockade: during rest and exercise in cold and hot environments. European Journal of Applied Physiology, 97(1) (2006) 43. – 31. WHELDON A, SAVINE RL, SONKSEN PH, HOLT RIG, Exercising in the cold inhibits growth hormone secretion by reducing the rise in core body temperature. Growth Hormone & Igf Research, 16(2) (2006) 125. – 32. FTAITI F, JEMNI M, KACEM A, ZAOUALI MA, TABKA Z, ZBIDI A, GRELOT L. Effect of hyperthermia and physical activity on circulating growth hormone. Appl Physiol Nutr Metab, 33 (2008) 880. – 33. TAMER K. Farklı Aerobik Antrenman Programlarının Serum Hormonları, Kan Lipidleri ve Vücut Yağ Yüzdesi Üzerine Etkisi, Beden Eğitimi Spor Bilimleri Dergisi, 1 (1996) 1. - 34. BRIDGE MW, ALLEN T, SHARMA A, JONES DA, Effect of ambient temperature on exercise-induced prolactinaemia. J Physiol, 521(P) (1999) 103. – 35. PAEZ LC, LUQUE GT, GUTIERREZ CV, OLTRAS CM, Prolactin responses to stress induced by a competitive swimming effort. Biology of Sport, 24(4) (2007) 311. – 36. MEEUSEN R, PIACENTINI MF, BUSSCHAERT B, BUYSE L, De SCHUTTER G, STRAY-GUNDERSEN J, Hormonal responses in athletes: the use of a two bout exercise protocol to detect subtle differences in (over)training status. European Journal of Applied Physiology, 91(2-3) (2004) 140. – 37. BRIDGE MW, WELLER AS, RAYSON M, JONES DA, Ambient temperature and the pituitary hormone responses to exercise in humans. Experimental Physiology, 88(5) (2003) 627. – 38. KOSKA J, ROVENSKY J, ZIMANOVA T, VIGAS M, Growth hormone and prolactin responses during partial and whole body warm-water immersions. Acta Physiologica Scandinavica, 178(1) (2003) 19. – 39. BRIDGE MW, WELLER AS, RAYSON M, Jones DA, Ambient temperature and the pituitary hormone responses to exercise in humans. Experimental Physiology, 88(5) (2003) 627. – 40. PITSILADIS YP, STRACHAN AT, DAVIDSON I, MAUGHAN RJ, Hyperprolactinaemia during prolonged exercise in the heat: evidence for a centrally mediated component of fatigue in trained cyclists. Experimental Physiology, 87(2) (2002) 215. – 41. LOW D, CABLE T, PURVIS A. Exercise thermoregulation and hyperprolactinaemia. Ergonomics, 48(11-14) (2005) 1547. – 42. BURK A, TIMPMANN S, KREEGIPUU K, TAMM M, UNT E, ÖÖPIK V. Effects of heat acclimation on endurance capacity and prolactin response to exercise in the heat. European Journal Of Applied Physiology, 112(12) (2012) 4091.