Izabela Luznik¹, Maja Pajek¹, Vedrana Sember¹, Ziva Majcen Rosker¹

¹University of Ljubljana, Faculty of Sport, Ljubljana, Slovenia

The Effectiveness of Cervical Sensorimotor Control Training for the Management of Chronic Neck Pain Disorders: A Systematic Review and Meta-Analysis

Monten. J. Sports Sci. Med. 2025, 14(1), Ahead of Prin | DOI: 10.26773/mjssm.250302

Abstract

This systematic review and meta-analysis aimed to evaluate the effectiveness of cervical sensorimotor control training for the management of chronic neck pain (NP) disorders compared to no treatment, or other conservative or non-conservative treatments. The review was conducted following the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guidelines (PROSPERO registration number: CRD42022381714). A comprehensive database search was performed (until November 2023) for randomized controlled trials (RCTs) and clinical trials evaluating the effects of cervical sensorimotor control training on several subjective and objective outcomes in adults with chronic NP (traumatic or non-traumatic origin). Data on study and patient characteristics, outcome measures, and effects on primary and secondary outcomes were extracted. Seven RCTs (409 participants) were included, of which 6 qualified for meta-analysis. Low-certainty evidence suggests that cervical sensorimotor control training is more effective for reducing pain (standardized mean difference (SMD): 0.48; 95% confidence interval (CI): 0.07 to 0.89) and improving cervicocephalic kinesthesia at short term than no treatment, and for reducing kinesiophobia at intermediate term compared to other treatment modalities. No significant between-group differences were found for other outcomes and follow-ups (very low-to-moderate-certainty evidence). Considering the significant improvements in cervicocephalic kinesthesia, cervical sensorimotor control training could be an important element in the rehabilitation of patients with chronic NP disorders. However, the current evidence in the literature is scarce to draw conclusions regarding its effectiveness as a stand-alone rehabilitation program.

Keywords

chronic neck pain, exercise, meta-analysis, neck kinesthesia, proprioception, sensorimotor control

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References

Ahern, M. M., Dean, L. V., Stoddard, C. C., Agrawal, A., Kim, K., Cook, C. E., & Garcia, A. N. (2020). The Effectiveness of Virtual Reality in Patients With Spinal Pain: A Systematic Review and Meta‐Analysis. Pain Practice, 20(6), 656–675. https://doi.org/10.1111/papr.12885

Alalawi, A., Devecchi, V., Gallina, A., Luque-Suarez, A., & Falla, D. (2022). Assessment of Neuromuscular and Psychological Function in People with Recurrent Neck Pain during a Period of Remission: Cross-Sectional and Longitudinal Analyses. Journal of Clinical Medicine, 11(7), 2042. https://doi.org/10.3390/jcm11072042

Armijo-Olivo, S., Costa, B. R. da, Cummings, G. G., Ha, C., Fuentes, J., Saltaji, H., & Egger, M. (2015). PEDro or Cochrane to Assess the Quality of Clinical Trials? A Meta-Epidemiological Study. PLOS ONE, 10(7), e0132634. https://doi.org/10.1371/journal.pone.0132634

Asiri, F., Reddy, R. S., Tedla, J. S., ALMohiza, M. A., Alshahrani, M. S., Govindappa, S. C., & Sangadala, D. R. (2021). Kinesiophobia and its correlations with pain, proprioception, and functional performance among individuals with chronic neck pain. PloS One, 16(7), e0254262. https://doi.org/10.1371/journal.pone.0254262

Bexander, C. S. M., & Hodges, P. W. (2023). Neck muscle activation in response to eye movement depends on sitting posture and is modified in whiplash associated disorders: Cross-sectional study. Musculoskeletal Science and Practice, 67, 102837. https://doi.org/10.1016/j.msksp.2023.102837

Bier, J. D., Scholten-Peeters, W. G. M., Staal, J. B., Pool, J., van Tulder, M. W., Beekman, E., Knoop, J., Meerhoff, G., & Verhagen, A. P. (2018). Clinical Practice Guideline for Physical Therapy Assessment and Treatment in Patients With Nonspecific Neck Pain. Physical Therapy, 98(3), 162–171. https://doi.org/10.1093/ptj/pzx118

Blanpied, P. R., Gross, A. R., Elliott, J. M., Devaney, L. L., Clewley, D., Walton, D. M., Sparks, C., & Robertson, E. K. (2017). Neck Pain: Revision 2017. The Journal of Orthopaedic and Sports Physical Therapy, 47(7), A1–A83. https://doi.org/10.2519/jospt.2017.0302

Bolton, P. S. (1998). The somatosensory system of the neck and its effects on the central nervous system. Journal of Manipulative and Physiological Therapeutics, 21(8), 553–563.

Boyd-Clark, L. C., Briggs, C. A., & Galea, M. P. (2002). Muscle spindle distribution, morphology, and density in longus colli and multifidus muscles of the cervical spine. Spine, 27(7), 694–701. https://doi.org/10.1097/00007632-200204010-00005

Cashin, A. G., & McAuley, J. H. (2020). Clinimetrics: Physiotherapy Evidence Database (PEDro) Scale. Journal of Physiotherapy, 66(1), 59. https://doi.org/10.1016/j.jphys.2019.08.005

Castellini, G., Pillastrini, P., Vanti, C., Bargeri, S., Giagio, S., Bordignon, E., Fasciani, F., Marzioni, F., Innocenti, T., Chiarotto, A., Gianola, S., & Bertozzi, L. (2022). Some conservative interventions are more effective than others for people with chronic non-specific neck pain: A systematic review and network meta-analysis. Journal of Physiotherapy, 68(4), 244–254. https://doi.org/10.1016/j.jphys.2022.09.007

Cetin, H., Kose, N., & Oge, H. K. (2022). Virtual reality and motor control exercises to treat chronic neck pain: A randomized controlled trial. Musculoskeletal Science and Practice, 62, 102636. https://doi.org/10.1016/j.msksp.2022.102636

Chiu, T. T. W., Law, E. Y. H., & Chiu, T. H. F. (2005). Performance of the craniocervical flexion test in subjects with and without chronic neck pain. The Journal of Orthopaedic and Sports Physical Therapy, 35(9), 567–571. https://doi.org/10.2519/jospt.2005.35.9.567

Cohen, S. P. (2015). Epidemiology, Diagnosis, and Treatment of Neck Pain. Mayo Clinic Proceedings, 90(2), 284–299. https://doi.org/10.1016/j.mayocp.2014.09.008

de Morton, N. A. (2009). The PEDro scale is a valid measure of the methodological quality of clinical trials: A demographic study. The Australian Journal of Physiotherapy, 55(2), 129–133. https://doi.org/10.1016/s0004-9514(09)70043-1

de Vries, J., Ischebeck, B. K., Voogt, L. P., van der Geest, J. N., Janssen, M., Frens, M. A., & Kleinrensink, G. J. (2015). Joint position sense error in people with neck pain: A systematic review. Manual Therapy, 20(6), 736–744. https://doi.org/10.1016/j.math.2015.04.015

de Zoete, R. M. J., Armfield, N. R., McAuley, J. H., Chen, K., & Sterling, M. (2021). Comparative effectiveness of physical exercise interventions for chronic non-specific neck pain: A systematic review with network meta-analysis of 40 randomised controlled trials. British Journal of Sports Medicine, 55(13), 730–742. https://doi.org/10.1136/bjsports-2020-102664

Demirbüken, İ., Özgül, B., Kuru Çolak, T., Aydoğdu, O., Sarı, Z., & Yurdalan, S. U. (2016). Kinesiophobia in relation to physical activity in chronic neck pain. Journal of Back and Musculoskeletal Rehabilitation, 29(1), 41–47. https://doi.org/10.3233/BMR-150594

Devecchi, V., Rushton, A. B., Gallina, A., Heneghan, N. R., & Falla, D. (2021). Are neuromuscular adaptations present in people with recurrent spinal pain during a period of remission? A systematic review. PLOS ONE, 16(4), e0249220. https://doi.org/10.1371/journal.pone.0249220

Ellis, P. (2010). The Essential Guide to Effect Sizes: Statistical Power, Meta-Analysis, and the Interpretation of Research Results. The Essential Guide to Effect Sizes: Statistical Power, Meta-Analysis, and the Interpretation of Research Results. https://doi.org/10.1017/CBO9780511761676

Espí-López, G. V., Aguilar-Rodríguez, M., Zarzoso, M., Serra-Añó, P., Fuente, J. M. M. D. L., Inglés, M., & Marques-Sule, E. (2021). Efficacy of a proprioceptive exercise program in patients with nonspecific neck pain: A randomized controlled trial. European Journal of Physical and Rehabilitation Medicine, 57(3), 397–405. https://doi.org/10.23736/S1973-9087.20.06302-9

Furlan, A. D., Malmivaara, A., Chou, R., Maher, C. G., Deyo, R. A., Schoene, M., Bronfort, G., van Tulder, M. W., & Editorial Board of the Cochrane Back, Neck Group. (2015). 2015 Updated Method Guideline for Systematic Reviews in the Cochrane Back and Neck Group. Spine, 40(21), 1660–1673. https://doi.org/10.1097/BRS.0000000000001061

Gallego Izquierdo, T., Pecos-Martin, D., Lluch Girbés, E., Plaza-Manzano, G., Rodríguez Caldentey, R., Mayor Melús, R., Blanco Mariscal, D., & Falla, D. (2016). Comparison of cranio-cervical flexion training versus cervical proprioception training in patients with chronic neck pain: A randomized controlled clinical trial. Journal of Rehabilitation Medicine, 48(1), 48–55. https://doi.org/10.2340/16501977-2034

Grassini, S. (2022). Virtual Reality Assisted Non-Pharmacological Treatments in Chronic Pain Management: A Systematic Review and Quantitative Meta-Analysis. International Journal of Environmental Research and Public Health, 19(7), 4071. https://doi.org/10.3390/ijerph19074071

Gross, A., Kay, T. M., Paquin, J.-P., Blanchette, S., Lalonde, P., Christie, T., Dupont, G., Graham, N., Burnie, S. J., Gelley, G., Goldsmith, C. H., Forget, M., Hoving, J. L., Brønfort, G., Santaguida, P. L., & Group, C. O. (2015). Exercises for mechanical neck disorders. Cochrane Database of Systematic Reviews, 1. https://doi.org/10.1002/14651858.CD004250.pub5

Guyatt, G., Oxman, A. D., Akl, E. A., Kunz, R., Vist, G., Brozek, J., Norris, S., Falck-Ytter, Y., Glasziou, P., DeBeer, H., Jaeschke, R., Rind, D., Meerpohl, J., Dahm, P., & Schünemann, H. J. (2011). GRADE guidelines: 1. Introduction-GRADE evidence profiles and summary of findings tables. Journal of Clinical Epidemiology, 64(4), 383–394. https://doi.org/10.1016/j.jclinepi.2010.04.026

Herbert, R., Moseley, A., & Sherrington, C. (1998). PEDro: A database of randomised controlled trials in physiotherapy. Health Information Management: Journal of the Health Information Management Association of Australia, 28(4), 186–188. https://doi.org/10.1177/183335839902800410

Higgins, J. P. T., Thomas, J., Chandler, J., Cumpston, M., Li, T., Page, M. J., & Welch, V.A. (Eds.). (2022) Cochrane Handbook for Systematic Reviews of Interventions (Version 6.3, updated February 2022). Cochrane. www.training.cochrane.org/handbook

Humphreys, B. K., & Irgens, P. M. (2002). The Effect of a Rehabilitation Exercise Program on Head Repositioning Accuracy and Reported Levels of Pain in Chronic Neck Pain Subjects. Journal of Whiplash & Related Disorders, 1(1), 99–112. https://doi.org/10.3109/J180v01n01_09

Hurwitz, E. L., Randhawa, K., Yu, H., Côté, P., & Haldeman, S. (2018). The Global Spine Care Initiative: A summary of the global burden of low back and neck pain studies. European Spine Journal, 27(6), 796–801. https://doi.org/10.1007/s00586-017-5432-9

Hutton, B., Salanti, G., Caldwell, D. M., Chaimani, A., Schmid, C. H., Cameron, C., Ioannidis, J. P. A., Straus, S., Thorlund, K., Jansen, J. P., Mulrow, C., Catalá-López, F., Gøtzsche, P. C., Dickersin, K., Boutron, I., Altman, D. G., & Moher, D. (2015). The PRISMA extension statement for reporting of systematic reviews incorporating network meta-analyses of health care interventions: Checklist and explanations. Annals of Internal Medicine, 162(11), 777–784. https://doi.org/10.7326/M14-2385

Jull, G. (2016). Discord Between Approaches to Spinal and Extremity Disorders: Is It Logical? The Journal of Orthopaedic and Sports Physical Therapy, 46(11), 938–941. https://doi.org/10.2519/jospt.2016.0610

Jull, G. A., Falla, D., Vicenzino, B., & Hodges, P. W. (2009). The effect of therapeutic exercise on activation of the deep cervical flexor muscles in people with chronic neck pain. Manual Therapy, 14(6), 696–701. https://doi.org/10.1016/j.math.2009.05.004

Jull, G. A., O’Leary, S. P., & Falla, D. L. (2008). Clinical assessment of the deep cervical flexor muscles: The craniocervical flexion test. Journal of Manipulative and Physiological Therapeutics, 31(7), 525–533. https://doi.org/10.1016/j.jmpt.2008.08.003

Jull, G., Falla, D., Treleaven, J., Hodges, P., & Vicenzino, B. (2007). Retraining cervical joint position sense: The effect of two exercise regimes. Journal of Orthopaedic Research, 25(3), 404–412. https://doi.org/10.1002/jor.20220

Kazeminasab, S., Nejadghaderi, S. A., Amiri, P., Pourfathi, H., Araj-Khodaei, M., Sullman, M. J. M., Kolahi, A.-A., & Safiri, S. (2022). Neck pain: Global epidemiology, trends and risk factors. BMC Musculoskeletal Disorders, 23(1), 26. https://doi.org/10.1186/s12891-021-04957-4

Knapp, G., & Hartung, J. (2003). Improved tests for a random effects meta-regression with a single covariate. Statistics in Medicine, 22(17), 2693–2710. https://doi.org/10.1002/sim.1482

Kristjansson, E., & Treleaven, J. (2009). Sensorimotor Function and Dizziness in Neck Pain: Implications for Assessment and Management. Journal of Orthopaedic & Sports Physical Therapy, 39(5), 364–377. https://doi.org/10.2519/jospt.2009.2834

Lin, R.-F., Chang, J.-J., Lu, Y.-M., Huang, M.-H., & Lue, Y.-J. (2010). Correlations between quality of life and psychological factors in patients with chronic neck pain. The Kaohsiung Journal of Medical Sciences, 26(1), 13–20. https://doi.org/10.1016/S1607-551X(10)70003-6

Liu, J.-X., Thornell, L.-E., & Pedrosa-Domellöf, F. (2003). Muscle Spindles in the Deep Muscles of the Human Neck: A Morphological and Immunocytochemical Study. Journal of Histochemistry & Cytochemistry, 51(2), 175–186. https://doi.org/10.1177/002215540305100206

Luque-Suarez, A., Martinez-Calderon, J., & Falla, D. (2019). Role of kinesiophobia on pain, disability and quality of life in people suffering from chronic musculoskeletal pain: A systematic review. British Journal of Sports Medicine, 53(9), 554–559. https://doi.org/10.1136/bjsports-2017-098673

Macedo, L. G., Elkins, M. R., Maher, C. G., Moseley, A. M., Herbert, R. D., & Sherrington, C. (2010). There was evidence of convergent and construct validity of Physiotherapy Evidence Database quality scale for physiotherapy trials. Journal of Clinical Epidemiology, 63(8), 920–925. https://doi.org/10.1016/j.jclinepi.2009.10.005

Maher, C. G., Sherrington, C., Herbert, R. D., Moseley, A. M., & Elkins, M. (2003). Reliability of the PEDro scale for rating quality of randomized controlled trials. Physical Therapy, 83(8), 713–721.

Mayoux-Benhamou, M. A., Revel, M., Vallée, C., Roudier, R., Barbet, J. P., & Bargy, F. (1994). Longus colli has a postural function on cervical curvature. Surgical and Radiologic Anatomy: SRA, 16(4), 367–371. https://doi.org/10.1007/BF01627655

McCaskey, M. A., Schuster-Amft, C., Wirth, B., Suica, Z., & Bruin, E. D. de. (2014). Effects of proprioceptive exercises on pain and function in chronic neck- and low back pain rehabilitation: A systematic literature review. BMC Musculoskeletal Disorders, 15(1), 382. https://doi.org/10.1186/1471-2474-15-382

Moher, D., Liberati, A., Tetzlaff, J., Altman, D. G., & PRISMA Group. (2009). Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement. Journal of Clinical Epidemiology, 62(10), 1006–1012. https://doi.org/10.1016/j.jclinepi.2009.06.005

Nolet, P. S., Côté, P., Kristman, V. L., Rezai, M., Carroll, L. J., & Cassidy, J. D. (2015). Is neck pain associated with worse health-related quality of life 6 months later? A population-based cohort study. The Spine Journal: Official Journal of the North American Spine Society, 15(4), 675–684. https://doi.org/10.1016/j.spinee.2014.12.009

Nusser, M., Kramer, M., Knapp, S., & Krischak, G. (2021). Effects of virtual reality-based neck-specific sensorimotortraining in patients with chronic neck pain: A randomized controlled pilot trial. Journal of Rehabilitation Medicine, 53(2). https://doi.org/10.2340/16501977-2786

Pedisic, Z., Pranic, S., & Jurakic, D. (2013). Relationship of Back and Neck Pain With Quality of Life in the Croatian General Population. Journal of Manipulative and Physiological Therapeutics, 36(5), 267–275. https://doi.org/10.1016/j.jmpt.2013.05.012

Peng, B., Yang, L., Li, Y., Liu, T., & Liu, Y. (2021). Cervical Proprioception Impairment in Neck Pain-Pathophysiology, Clinical Evaluation, and Management: A Narrative Review. Pain and Therapy, 10(1), 143–164. https://doi.org/10.1007/s40122-020-00230-z

Pérez-Cabezas, V., Ruiz-Molinero, C., Jimenez-Rejano, J. J., Chamorro-Moriana, G., Gonzalez-Medina, G., & Chillon-Martinez, R. (2020). Effectiveness of an Eye-Cervical Re-Education Program in Chronic Neck Pain: A Randomized Clinical Trial. Evidence-Based Complementary and Alternative Medicine, 2020, 1–9. https://doi.org/10.1155/2020/2760413

Petersen, C. M., Zimmermann, C. L., & Tang, R. (2013). Proprioception interventions to improve cervical position sense in cervical pathology. International Journal of Therapy and Rehabilitation, 20(3), 154–163.

Proske, U., & Gandevia, S. C. (2012). The Proprioceptive Senses: Their Roles in Signaling Body Shape, Body Position and Movement, and Muscle Force. Physiological Reviews, 92(4), 1651–1697. https://doi.org/10.1152/physrev.00048.2011

Qu, N., Tian, H., Martino, E. D., & Zhang, B. (2022). Neck Pain: Do We Know Enough About the Sensorimotor Control System? Frontiers in Computational Neuroscience, 16, 946514. https://doi.org/10.3389/fncom.2022.946514

R Core Team. (2023). R: A Language and Environment for Statistical Computing. R Foundation for Statistical Computing. https://www.R-project.org/

Rasmussen-Barr, E., Halvorsen, M., Bohman, T., Boström, C., Dedering, Å., Kuster, R. P., Olsson, C. B., Rovner, G., Tseli, E., Nilsson-Wikmar, L., & Grooten, W. J. A. (2023). Summarizing the effects of different exercise types in chronic neck pain—A systematic review and meta-analysis of systematic reviews. BMC Musculoskeletal Disorders, 24(1), 806. https://doi.org/10.1186/s12891-023-06930-9

Reddy, R. S. Y., Maiya, A. G., Rao, S. K., Alahmari, K. A., Tedla, J. S., Kandakurti, P. K., & Kakaraparthi, V. N. (2021). Effectiveness of Kinaesthetic Exercise program on Position Sense, Pain, and Disability in Chronic Neck Pain Patients with Cervical Spondylosis – A Randomized Comparative Trial. Physikalische Medizin, Rehabilitationsmedizin, Kurortmedizin, 31(4), 242–250. https://doi.org/10.1055/a-1290-9556

Revel, M., Minguet, M., Gergoy, P., Vaillant, J., & Manuel, J. L. (1994). Changes in cervicocephalic kinesthesia after a proprioceptive rehabilitation program in patients with neck pain: A randomized controlled study. Archives of Physical Medicine and Rehabilitation, 75(8), 895–899. https://doi.org/10.1016/0003-9993(94)90115-5

Rezaei, I., Razeghi, M., Ebrahimi, S., Kayedi, S., & Zadeh, A. R. (2018). A Novel Virtual Reality Technique (Cervigame®) Compared to Conventional Proprioceptive Training to Treat Neck Pain: A Randomized Controlled Trial. Journal of Biomedical Physics and Engineering. https://doi.org/10.31661/jbpe.v0i0.556

Röijezon, U., Clark, N. C., & Treleaven, J. (2015). Proprioception in musculoskeletal rehabilitation. Part 1: Basic science and principles of assessment and clinical interventions. Manual Therapy, 20(3), 368–377. https://doi.org/10.1016/j.math.2015.01.008

Rudolfsson, T., Björklund, M., & Djupsjöbacka, M. (2012). Range of motion in the upper and lower cervical spine in people with chronic neck pain. Manual Therapy, 17(1), 53–59. https://doi.org/10.1016/j.math.2011.08.007

Rudolfsson, T., Djupsjöbacka, M., Häger, C., & Björklund, M. (2014). Effects of neck coordination exercise on sensorimotor function in chronic neck pain: A randomized controlled trial. Journal of Rehabilitation Medicine, 46(9), 908–914. https://doi.org/10.2340/16501977-1869

Ruhe, A., Fejer, R., & Walker, B. (2011). Altered postural sway in patients suffering from non-specific neck pain and whiplash associated disorder—A systematic review of the literature. Chiropractic & Manual Therapies, 19, 13. https://doi.org/10.1186/2045-709X-19-13

Saadat, M., Salehi, R., Negahban, H., Shaterzadeh, M. J., Mehravar, M., & Hessam, M. (2019). Traditional physical therapy exercises combined with sensorimotor training: The effects on clinical outcomes for chronic neck pain in a double-blind, randomized controlled trial. Journal of Bodywork and Movement Therapies, 23(4), 901–907. https://doi.org/10.1016/j.jbmt.2019.02.016

Safiri, S., Kolahi, A.-A., Hoy, D., Buchbinder, R., Mansournia, M. A., Bettampadi, D., Ashrafi-Asgarabad, A., Almasi-Hashiani, A., Smith, E., Sepidarkish, M., Cross, M., Qorbani, M., Moradi-Lakeh, M., Woolf, A. D., March, L., Collins, G., & Ferreira, M. L. (2020). Global, regional, and national burden of neck pain in the general population, 1990-2017: Systematic analysis of the Global Burden of Disease Study 2017. BMJ, 368, m791. https://doi.org/10.1136/bmj.m791

Sarig Bahat, H., Croft, K., Carter, C., Hoddinott, A., Sprecher, E., & Treleaven, J. (2018). Remote kinematic training for patients with chronic neck pain: A randomised controlled trial. European Spine Journal, 27(6), 1309–1323. https://doi.org/10.1007/s00586-017-5323-0

Sarig Bahat, H., Takasaki, H., Chen, X., Bet-Or, Y., & Treleaven, J. (2015). Cervical kinematic training with and without interactive VR training for chronic neck pain – a randomized clinical trial. Manual Therapy, 20(1), 68–78. https://doi.org/10.1016/j.math.2014.06.008

Sremakaew, M., Jull, G., Treleaven, J., & Uthaikhup, S. (2023). Effectiveness of adding rehabilitation of cervical related sensorimotor control to manual therapy and exercise for neck pain: A randomized controlled trial. Musculoskeletal Science and Practice, 63, 102690. https://doi.org/10.1016/j.msksp.2022.102690

Stanton, T. R., Leake, H. B., Chalmers, K. J., & Moseley, G. L. (2016). Evidence of Impaired Proprioception in Chronic, Idiopathic Neck Pain: Systematic Review and Meta-Analysis. Physical Therapy, 96(6), 876–887. https://doi.org/10.2522/ptj.20150241

Sterling, M., de Zoete, R. M. J., Coppieters, I., & Farrell, S. F. (2019). Best Evidence Rehabilitation for Chronic Pain Part 4: Neck Pain. Journal of Clinical Medicine, 8(8), Article 8. https://doi.org/10.3390/jcm8081219

Tejera, D., Beltran-Alacreu, H., Cano-de-la-Cuerda, R., Hernández, J. V. L., Martín-Pintado-Zugasti, A., Calvo-Lobo, C., Gil-Martínez, A., & Fernández-Carnero, J. (2020). Effects of Virtual Reality versus Exercise on Pain, Functional, Somatosensory and Psychosocial Outcomes in Patients with Non-specific Chronic Neck Pain: A Randomized Clinical Trial. International Journal of Environmental Research and Public Health, 17(16), 5950. https://doi.org/10.3390/ijerph17165950

Treleaven, J. (2008). Sensorimotor disturbances in neck disorders affecting postural stability, head and eye movement control. Manual Therapy, 13(1), 2–11. https://doi.org/10.1016/j.math.2007.06.003

Uluğ, N., Yakut, Y., Alemdaroğlu, İ., & Yılmaz, Ö. (2016). Comparison of pain, kinesiophobia and quality of life in patients with low back and neck pain. Journal of Physical Therapy Science, 28(2), 665–670. https://doi.org/10.1589/jpts.28.665

Viechtbauer, W. (2005). Bias and Efficiency of Meta-Analytic Variance Estimators in the Random-Effects Model. Journal of Educational and Behavioral Statistics, 30(3), 261–293. https://doi.org/10.3102/10769986030003261

Wan, X., Wang, W., Liu, J., & Tong, T. (2014). Estimating the sample mean and standard deviation from the sample size, median, range and/or interquartile range. BMC Medical Research Methodology, 14(1), 135. https://doi.org/10.1186/1471-2288-14-135

Wang, X., Qu, N., Wang, Y., Dong, J., Jiao, J., & Wu, M. (2022). Effects of experimental pain on the cervical spine reposition errors. BMC Musculoskeletal Disorders, 23(1), 259. https://doi.org/10.1186/s12891-022-05170-7